CARD: the Canadian AMR database presented to the ABRomics platform

On June 24, Emilie Bordeleau presented to the ABRomics Consortium, her work on the development of antimicrobial resistance ontologies associated with CARD (Comprehensive Antibiotic Resistance Database), the Canadian database and analysis platform dedicated to monitoring antimicrobial resistance genes. Discover the video of her presentation below :

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Emilie Bordeleau is leading an interdisciplinary, cross-Canada research project that is building upon the successful Comprehensive Antibiotic Resistance Database (CARD). This unique database and software platform is used globally in the genomic surveillance of antimicrobial resistance genes (ARGs), providing high-quality DNA and protein reference sequences, detection models and bioinformatics tools.

Leveraging the ontological expertise of her colleagues at Simon Fraser University and her extensive biochemical knowledge of AMR mechanisms, Emilie B. is developing controlled vocabularies for CARD that will enable effective data exchange and integration across the broader scientific community. Furthermore, she is expanding CARD’s knowledge framework by creating and integrating controlled vocabularies that describe MGEs. Capturing the relationships between ARGs and factors involved in their mobility is essential to improve risk assessment and mitigation strategies.

A collaboration between the Canadian research groups and the ABRomics team is starting this automn to enhance and integrate CARD’s controlled vocabularies into ABRomics bacterial genomic data workflows. Together, we aim to establish a model for international collaboration, demonstrating the transformative potential of harmonized data frameworks and standardized outputs to drive global health initiatives forward.